The Facts About an Enlarged Prostate

An enlarged prostate is a problem most men will confront in their lifetimes. If a man lives long enough, he’ll most likely have an enlarged prostate.

The prostate is a male reproductive gland tasked with producing the fluid that carries sperm out of the body during ejaculation. The prostate surrounds the urethra, the tube through which urine passes during urination. As men age, the prostate gland grows bigger. It is originally about the size of a walnut, often increasing in size by the age of 40 to the size of an apricot. By the time a man is 60 years old, his prostate gland may have enlarged to the size of a lemon. The enlarged prostate ends up squeezing the urethra like a clamp on a garden hose, causing the flow of urine to become weak and slow. The condition is also known as benign prostatic hyperplasia. It’s not cancerous, and it doesn’t increase a man’s risk of contracting prostate cancer. More than 50 % of men in their sixties have symptoms of enlarged prostates due to benign prostatic hyperplasia, and that number rises to many as 90 percent when men reach their seventies and eighties.

Why Enlarged Prostate Occurs

The causes of enlarged prostate are not well understood. The only two risk factors doctors have been able to associate with enlarged prostate are growing old and having a functioning set of testicles. Men who have had their testicles removed when they were young do not develop benign prostatic hyperplasia.

Other explanations for an enlarged prostate include:

  • Decreased testosterone level. The amount of testosterone in the blood decreases as a man ages. When that occurs, the proportion of naturally occurring estrogen in a man’s body increases, and may promote growth of the prostate.
  • Increased DHT level. The prostate derives a substance called dihydrotestosterone, or DHT, from testosterone. Even though blood testosterone levels drop in older men, DHT production doesn’t slow down, so high levels of DHT continue to build up in the prostate. This could lead to the growth of prostate cells.
  • Genetics. It has also been suggested that genetic instructions inside some prostate cells may order them to activate later in life and begin to grow.

An enlarged prostate also can result from a prostate infection or from prostate cancer, although those occur less frequently and are not as inevitable as BPH.

The symptoms of enlarged prostate always revolve around a problem with the ability to urinate. Men might find that they can only maintain a hesitant, weak stream that frequently stops. They also may need to urinate more frequently, because the bladder is not completely emptied with each episode of urination, particularly at night. There is usually no pain involved in BPH; if there is pain, it could mean an infection has occurred.

There’s no way to prevent benign prostatic hyperplasia. It occurs as a function of aging.

Enlarged Prostate: Diagnosis and Treatment

The means used by physicians to diagnose an enlarged prostate include:

  • Rectal exam. The prostate gland can best be felt through the rectal cavity. A doctor inserts a gloved, lubricated finger into your rectum to feel how large the prostate gland is, and whether there are any abnormalities, such as an area that is hard or lumpy.
  • Urine and blood tests. Results of a urine test can suggest that the prostate may be enlarged due to infection, while a blood test can measure prostate specific antigen (PSA), which is high when prostate cancer is present. The United States Preventive Services Task Force recently recommended against PSA tests for prostate cancer, but many medical experts say men should still get screened. PSA tests may also be used to calculate PSA density, which is your PSA score divided by the size of your prostate (determined through ultrasound). A high PSA density is more likely to be indicative of cancer; a low PSA density suggests prostate enlargement.
  • Ultrasound exam. Sound waves are directed at the prostate through a probe inserted in the rectum. The echoes of these sounds waves then create an image of the prostate on a television screen.
  • Urine flow exam. You urinate into a special device that gauges the speed and strength of urine flow.
  • Cystoscopy. A small tube is inserted into the penis through the urethra, allowing a doctor to see the inside of the urethra and bladder, and to visualize areas compressed by an enlarged prostate.

Benign prostatic hyperplasia-related enlarged prostate is most often treated through drug therapy or surgery:

  • Drug therapy. Medications known as alpha-blockers relieve pressure and restore urine flow by relaxing the muscles near the prostate. They don’t reduce the size of the prostate, however. Another drug known as Proscar (finasteride) is able to reduce the size of the prostate gland by blocking an enzyme that normally interacts with testosterone to stimulate prostate growth. By stopping this interaction, finasteride slows the growth of the prostate gland and even reduces the size of the prostate, which could reduce blockage.
  • Surgery. There are several surgical options for treating BPH-related enlarged prostate. In extreme cases, the prostate may be removed. A more common surgical approach — accounting for 90 percent of benign prostatic hyperplasia surgeries — is to widen the urethra by trimming excess tissue away from the gland. This option generally doesn’t cause some of the complications of other prostate surgeries, such as incontinence and impotence.

Unfortunately, an enlarged prostate can reoccur after surgery that trims excess prostate tissue, or if a man stops taking his medication. Untreated enlarged prostate can lead to urinary tract infections, kidney or bladder stones, or urinary retention and kidney damage. That’s why it’s so important to see a doctor if you have symptoms that may suggest a prostate problem.


Testosterone Therapy is Safe for Prostate Cancer

Testosterone therapy does not increase the risk of prostate cancer. Evidence suggests that testosterone therapy does not increase the risk of developing prostate cancer nor that it converts indolent prostate disease into clinically significant disease.

Medical studies involving anabolic steroids have failed to show prostate conditions or even prostate markers worsen with anabolic steroid treatment. Elevated anabolic steroid levels induced in men younger than 40 years of age have not shown a significant increase in prostate problems, prostate size or prostate-specific antigen (PSA) in multiple studies, even at supraphysiological doses. In fact, Cooper et al. concluded in their study that “Serum PSA is not responsive to elevated serum testosterone levels in healthy young men”. 187 hypogonadal male subjects above 45 years of age treated with anabolic steroids experienced no significant change in PSA or prostate disease after one year of therapy. In a randomized, double-blind, placebo-controlled trial, 44 hypogonadal men aged 44 to 78 years received anabolic steroids or matching placebo for 6 months. Prostate biopsies performed before and after therapy showed no treatment-related change in prostate histology, tissue biomarkers, gene expression, or cancer incidence or severity. Eleven hypogonadal men with a median age of 36 years were treated with anabolic steroid trans-scrotal patches for 7 to 10 years. No relevant changes occurred in clinical chemistry, hemoglobin and erythrocyte counts, prostate volume or prostate disease, and bone density increased slightly during the observation period. Prostate-specific antigen levels were constantly low in all patients, and the authors concluded long-term anabolic steroid therapy for male hypogonadism is safe. A placebo-controlled study in 13 hypogonadal men aged 57 to 76 years old demonstrated three months of anabolic steroid treatments resulted in an increase in lean body mass, no increase in prostate disease and possibly a decline in bone resorption. The authors also observed some effect on serum lipoproteins, hematological parameters, and only a slight sustained increase in serum PSA levels. A short- term study on men over 70 years of age showed no ill effects on prostate size, symptoms or PSA levels with either transdermal or intramuscular anabolic steroid treatment. The longer-follow up investigation of the previously mentioned study showed no significant increase of PSA levels after one year of transdermal anabolic steroid use and resulted in no change in signs or symptoms of prostate hyperplasia. One year of anabolic steroid treatments in 48 hypogonadal men resulted in a mild increase in most of the hypogonadal men’s PSA values without observation of increased prostate disease.

Another study monitored 81 hypogonadal men for a mean of 34 months taking testosterone therapy and showed normalized testosterone levels, improved cardiovascular effect, improved sexual function and better overall quality of life. The incidence of prostate cancer among men with hypogonadism receiving testosterone treatment “is no greater than that of the general population”.

Since testosterone trials have failed to show any significant increase in prostate cancer rates, testosterone therapy “may not even be harmful in men undergoing surveillance for low-risk PCa”

In men at high risk for developing prostate cancer (with and without a history of high grade prostatic intraepithelial neoplasia), anabolic steroid treatments were provided for 12 months. Of the 75 men, prostate cancer was identified with biopsy in one man and represents a 1.3% prostate cancer risk overall, which is not beyond the population background prevalence. The results do not suggest an abrupt increase of prostate cancer growth or development in patients administered anabolic steroid therapy. Thus, anabolic steroid treatments are not contraindicated in men with this type of high risk for developing prostate cancer.

Testosterone therapy in men with previous prostate cancer did not produce increased disease recurrence. No ill effects from anabolic steroid administration in hypogonadal men previously treated for prostate cancer were observed for periods up to 12 years in 17 men, including prostate cancer recurrence. Patients with organ-confined prostate cancer after radical prostatectomy experienced no PSA recurrences or increases after a median of 19 months of anabolic steroid therapy. 31 hypogonadal men received anabolic steroid treatments after prostate brachytherapy for a median of 4.5 years without cancer recurrence or documented cancer progression.

A 52-year-old man after radical prostatectomy was given adjuvant external beam radiation and LH-RH agonist therapy for PSA level recurrence. The treatment and disease progression resulted in sustained loss of libido, hot flashes and depression. After 16 months of no PSA recurrence, he was treated with anabolic steroids, which produced significant relief of symptoms and no increase in PSA. Sustained anabolic steroids were required to alleviate the patient’s symptoms.

“In another case, a 63-year-old man with prostate cancer and PSA 5.0 ng/ml underwent radical prostatectomy with findings of Gleason 7/10 and one seminal vesicle involved with cancer. He then received three successive 3-month gosereline injections and adjuvant radiotherapy. One year after surgery he complained of poor libido and hot flushes; PSA was undetectable but serum testosterone was in the castrate range at 28ng/dl. At 3 months, when PSA remained undetectable and testosterone still measured only 45ng/dl, he was started on 1% testosterone gel 5 g/day. Hypogonadal symptoms improved rapidly, and at follow-up, 26 months after surgery and 20 months after his last LH-RH agonist administration, he still remains hypogonadal (testosterone 194 ng/dl) and uses testosterone gel every 2 days”.

“Despite the wide spread of contraindication of testosterone replacement in men with known or suspected PCa, there is no convincing evidence that the normalization of testosterone serum levels in men with low but no castrate levels is deleterious”. “The available literature suggests that testosterone therapy is reasonable for patients who have received curative therapy for prostate cancer and that testosterone therapy does not jeopardize cancer control in patients suffering from symptomatic hypogonadism”. One hundred and eleven men were monitored in six uncontrolled studies with testosterone therapy after surgical or radiation treatment for prostate cancer and only two experienced disease recurrence. “Anecdotal evidence suggests that testosterone therapy does not necessarily cause increased prostate specific antigen even in men with untreated prostate cancer”.


Viagra is found potential in Treating Atherosclerosis

Viagra has been an essential medication in the medical field. The discovery of Sildenafil Citrate which is the active constituent of this medication has helped the erectile dysfunction afflicted sector of the society. Viagra is highly adopted as a treatment for erectile dysfunction. This condition is a physical malfunction affecting the phallus of the afflicted man and is also known as impotence in men. This physical malfunction disables a man from achieving stiffness of his phallus which keeps him from enjoying a successful session of coital activity and causes annoyance to the female partner as she is frequently left unsatisfied.

Viagra is considered efficient due to excellent success rate and assured results. But through the course of time the medical industry has seen many uses of Viagra, calling it a versatile medication. Initially, before Sildenafil citrate was marked for erectile dysfunction, it was devised with the intention of discovering treatment for hypertension and angina pectoris. But during clinical trials, it was noticed that the compound has enormous influence on the erectile function than on the intended symptoms; hence, it can be assumed that Sildenafil citrate or
Viagra can be used for other treatments due to its influence on the blood circulation of the body.

The latest use or added advantage of Viagra is that it is used in the treatment of Atherosclerosis. The disease affecting the arterial blood vessels is called as Atherosclerosis. In common words it is called as hardening or furring of the arteries. The hardening of the arteries is caused by the formation and deposition of plaque in the arteries. Plaque deposited in the wall of arteries consists of cholesterol crystals, macrophage white blood cells, and dead cells.Thus the less amount of blood is supplied to the heart and can cause heart problems.

The cause for the erectile dysfunction was the less amount of blood supply to the penis at the time of sexual activity. Viagra increases the supply of blood to the penis during the intercourse by inhibition of phosphodiesterase enzyme. Thus the erectile dysfunction is not caused because men get the erection that lasts for the sufficient time during the sexual intercourse. Viagra, when increases the blood flow to the penis then it can simultaneously increase the blood flow to the all other parts in the body.

A recent research ascertained that, people who are suffering from atherosclerosis and are taking Viagra experienced increased blood supply. Due to the increased in blood circulation the plaque which was accumulated in the arterial walls were truncated and vanished. The study was conducted with involvement of 200 atherosclerosis affected men who were treated with dosage of Viagra for a number of days. After testing these men, significant improvement in the condition atherosclerosis was noticed. During diagnoses, x-ray images of these men were captured which indicated plaque free arterial walls, which denoted that increased blood flow resulted in cleansing of these walls.

On the basis of such studies researches are quite confirmed that Viagra can certainly play an important part in atherosclerosis treatment techniques. However, it is essential to consult a doctor to determine your complete health condition before you take Viagra for whatsoever reason.


Anabolic Steroids, PDE-5 Inhibitors and the Bedroom

Ever since revolutionizing the market in 1998, PDE-5 inhibitors have impacted American culture in ways that could not have initially been foreseen. Originally released for the treatment of erectile dysfunction, it did not take long for the general public to realize that this class of drugs had applications outside of those indicated for the target demographic. Within a short period of time, their accepted use expanded to include performance enhancement as well as the medical treatment of ED. No longer viewed an “old man’s” drug, the social stigma attached to these compounds was lifted and in the process, their use permeated nearly every sector of society.

Instead of elaborating on the numerous potential applications of PDE-5 inhibitors in the general population, I want to shift focus and discuss the unique challenges a anabolic steroid-using bodybuilder might face and how these drugs can assist in overcoming them. One issue common to the steroid user, when utilizing particular anabolic steroids, is that of sexual dysfunction.

It is no secret that certain anabolic steroids can cause both libido and performance issues and for many, ancillary supplementation is required in order to treat the condition effectively. For those who find themselves on the other end of the spectrum, with a libido that just won’t quit, PDE-5 inhibitors will offer you the ability to keep pace with your desire, transforming you into a virtual sexual superman. So, whether you seek relief from the crippling effects of anabolic steroids or you simply want to elevate your game to the next level, PDE-5 drugs will provide you with the effects you’re looking for.

PDE-5 drugs work to increase erection capacity by enhancing vasodialation. This is accomplished by inhibiting the phosphodiesterase type 5 (PDE-5) enzyme, which in turn increases levels of cGMP mediated nitric oxide. The end result is increased blood flow to the penis, allowing the individual to achieve and sustain better quality erections for a longer period of time. The 1st PDE-5 inhibitor to be released was Viagra (chemical name, Sildenafil) and to this day, it still works the best for the largest percentage of people. Viagra hits hard and fast, with an onset of action of about 30 minutes and optimal effects being achieved at the 60-90 minute mark. However, unlike other PDE-5’s, it has a relatively short window of opportunity, providing a strong therapeutic effect for about 4-6 hours. This makes Viagra ideal for those individuals who have more control over their sex lives, such as married couples or those who know when they will be engaging in sexual activity. For those who are unable to plan ahead of time, it may be wise to explore less limiting options.

Along with Viagra’s typically superior performance comes both a higher rate and greater intensity of side effects. Tolerability can vary greatly, with some individuals experiencing little in the way of negative side effects, while others find them bothersome enough to switch to another drug. Most commonly, they are limited to headache, flushing, stuffy nose, increased intraocular pressure, and blurred vision; similar to what one might experience with a head cold. Many find relief from these side effects by administering a decongestant prior to use, which I highly recommend, as being unable to breathe through one’s nose is not a situation particularly well suited to close quarter sexual contact. Rarely, more serious adverse events have occurred, such as priapism, severe hypotension, myocardial infarction (heart attack), ventricular arrhythmias, stroke, , and sudden hearing loss. The generally recommended dosing range falls between 50-100 mcg, although some may find lower doses to be adequate. For best results, Viagra should not be taken with a high-fat meal, as dietary fat can impair absorption. Best results are achieved when the drug is administered on an empty stomach.

Nicknamed the “weekend warrior”, Cialis was released in 2003 and quickly became a popular alternative to Viagra because of its long half-life life in the body. While not as potent as Viagra per effective dose, it remains active for about 36 hours, allowing for greater spontaneity in one’s love life. However, Cialis’s onset of action is more prolonged, taking a few hours to reach peak effectiveness. Unlike the other PED-5 inhibitors, the absorption of Cialis is not hindered by fat intake, allowing for freedom in one’s diet around the time of administration. This can come in handy when plans are made unexpectedly. Standard dosing is 10-40 mg, with 20 mg being sufficient for most people. Side effects with Cialis are generally much milder compared to Viagra, further increasing its appeal.

The last available PED-5 inhibitor we are going to discuss is Levitra, also known as Vardenafil. In many ways Levitra is similar to Viagra, in that both possess a rapid onset of action (Cialis beats Viagra at 20 minutes), a relatively short half-life (4-5 hours), and a hard-hitting pro-sexual effect. However, there are some significant differences between the two. Research shows that Levitra, despite a nearly identical half-life, exerts its beneficial effects for a longer period of time, in addition to providing a stronger therapeutic effect per mg. For the most part, Levitra is well tolerated, with nausea being the most commonly reported side effect. Rarely, side effects such as photosensitivity, altered vision, abdominal pain, hypotension, palpitation, tachycardia, and priapism can occur. Normal dosing ranges between 10-20 mg, taken 60-90 minutes before sexual activity.

Fortunately, all of these performance enhancers are widely available on the grey market, with numerous peptide-research companies offering them at significantly reduced prices compared to their pharmaceutical counterparts. As a whole, this category of drugs exhibits a strong safety profile, with serious side effects occurring only rarely in healthy men. Whether you’re trying to restore what was lost or simply enhance your current performance, PDE-5 inhibitors are the best drugs for this purpose.


Male Menopause Affects More Than Five Million Men

While most frequently associated with women’s health, age-related hormone changes, often dubbed menopause, can occur in men as well, causing symptoms of fatigue, mood swings, decreased desire for sex, hair loss, lack of concentration and weight gain. Experts estimate that more than 5 million men are affected, yet worry the number may be considerably higher since symptoms are frequently ignored.

Male hypogonadism, as it’s referred to in the medical community, occurs when the testicles do not produce enough testosterone, the hormone that plays a key role in masculine growth and development. When hormone levels drop, men can experience significant mental and physical changes.

“This is a highly prevalent disorder,” said Robert Brannigan, MD, urologist at Northwestern Memorial Hospital. “Unfortunately, we estimate that 95 percent of cases are undiagnosed and therefore untreated. When ignored, symptoms can seriously disrupt one’s quality of life.”

“My body was telling me that something wasn’t right. I was always tired, it didn’t matter how much sleep I got, I constantly wanted to take a nap,” said Michael Andruzzi, a 40 year old man diagnosed with male hypogonadism and a patient at Northwestern Memorial.

Brannigan explains hormone variations are a normal aspect of getting older. “In females, ovulation comes to an end and hormone production declines in a relatively quick period of time, whereas men experience hormone shifts more slowly, with testosterone levels dropping around one percent each year beginning in a man’s late thirties,” adds Brannigan, who is also an associate professor of urology at the Northwestern University Feinberg School of Medicine.

Brannigan goes on to explain that by age seventy, the reduction in a male’s testosterone level could be as high as fifty percent or more compared to baseline levels, but notes that aging men are not the only ones at risk. A number of genetic causes can impact males from birth and are usually diagnosed with failure to progress normally through puberty during the teenage years.

Treatment options for male hypogonadism include hormone replacement therapy (HRT) via absorbable pellet implants, topical gels, patches, and injections. Through HRT, doctors can restore sexual function and muscle strength. In addition, men often experience an increase in energy and an improved overall sense of well-being.

“Once I began treatment, I felt better very quickly,” said Andruzzi. “My energy level shot back up; I regained strength and felt I could concentrate much better.”

“We are seeing more men affected by male hypogonadism than we saw ten years ago,” said Brannigan. “However, many men continue to suffer in silence due to a lack of awareness surrounding the disorder. Because male hypogonadism can significantly impact the quality of one’s life, it’s important that men pay attention to their body and openly discuss symptoms with their physician in order to prevent overlooking the cause and avoid missing an opportunity for appropriate therapy.”

Although research to determine the exact association continues, doctors also warn that male hypogonadism has been linked to chronic medical conditions such as high cholesterol, diabetes and cardiovascular disease. It’s also closely associated with infertility.

“This disorder is not something that should be ignored,” said Brannigan, who is working to educate patients and physicians about the symptoms and treatments available in order to ensure therapies are made available to men in need.

Male hypogonadism is most commonly diagnosed through a simple blood test. Brannigan notes hormone replacement therapy is not appropriate for all patients especially those with history of prostate and breast cancer and men trying to conceive. He suggests consulting your doctor if you are experiencing symptoms.


Viagra and Diabetes

Viagra can be used to try and solve the many erectile problems which are caused by diabetes. It is only safe to use this method of treatment as long as your diabetes is properly monitored and under control and it is extremely important that you make sure that you have had help and guidance from your GP about your condition and the best way to treat its side effects. A recent study which looked at the success rate of Viagra in diabetic men found that there was an increase of ‘successful intercourse attempts’ by 26.7%.

Viagra can help reduce your diabetic induced erectile problems by enhancing the effects of nitric oxide, relaxing the muscles around the penis and pelvic area and most importantly to increase the blood flow by widening the blood vessels surrounding the penis.

If you suffer from diabetes there are some side effects which you should especially look out for is sudden loss of sight and suffering from flu like symptoms. Diabetic men are also more likely to suffer from the side effect of dizziness and it is more likely to be more severe than the dizziness that non diabetic men would suffer from. The dizziness could also be enhanced by some diabetes treatments like Metformin. If you have diabetes you are also more likely to suffer from excessive swelling of the hands and feet whilst taking Viagra and again this could be caused by the medication which you have been prescribed to control your blood sugar levels.


How to Cope With Erectile Dysfunction

You may fear that having erectile dysfunction (ED) makes you less of a man and, as a result, are ashamed to bring it up. But talking about it with your partner and your physician is the first step toward coping with a very common condition.

Erectile dysfunction is defined as the inability to achieve or sustain an erection for sexual intercourse. As many as 30 million men in the United States have erectile dysfunction, according to the Urology Care Foundation of the American Urological Association. “There is certainly less of a stigma now, and men seem more confident speaking with their physicians because of the fact that there are several available therapies,” says Daniel A. Shoskes, MD, urologist at The Glickman Urological and Kidney Institute at Cleveland Clinic in Ohio. The availability of drugs such as Viagra, Levitra, and Cialis have made erectile dysfunction, or ED, something of a household name.

Dr. Shoskes says that the time to seek medical help to cope with erectile dysfunction is when it is occurring in a persistent way and interfering with your quality of life.

“It is worthwhile to start the conversation with a physician to see the state of your general health and see what can be done for the libido and sex drive,” says Shoskes.

Sometimes erectile dysfunction is caused by stress or other emotional issues, but it can also be the first sign of a potentially serious vascular disease. “New onset of erectile dysfunction in a middle-aged man can often herald the development of blood vessel disease anywhere in the body, and should prompt a visit to your internist or preventive cardiologist,” he says.

A recent study shows that men with erectile dysfunction are more likely to have heart disease and to die from it. The worse the erectile dysfunction, the greater these risks, the study showed.

This is why merely talking about erectile dysfunction can be lifesaving. If you have vascular disease, make sure you are doing everything you can for vascular health including stopping smoking and getting control of blood pressure, cholesterol, and blood sugar levels,” Shoskes says.

Bruce R. Gilbert, MD, PhD,the director of reproductive and sexual medicine at the North Shore LIJ’s Smith Institute for Urology in Lake Success, N.Y., confirms that erectile dysfunction affects more than just quality of life. “It often precedes the diagnosis of heart disease or another vascular disease, such as diabetes, by two to ten years. Erection problems can be a harbinger of more significant cardiovascular problems down the road,” Dr. Gilbert says.

“We have changed from giving out pills to treat ED to making sure that we figure out what is going on,” he says. “It’s not an embarrassment, and it might portend something else that you now have the opportunity to take care of.” “The way to cope with erectile dysfunction is to get help,” says Diana Londoño, MD, a urologist at Kaiser Permanente in Los Angeles. Start with your primary care doctor who can then decide if you need a referral to a urologist, a vascular specialist, or possibly a mental health counselor.

Therapy may help uncover personal issues such as performance anxiety or relationship issues that contribute to ED. Your therapist will help with developing coping strategies to address these issues.

It’s also important to discuss erectile dysfunction with your partner. “Be honest,” recommends Dr. Londoño. “Tell her that you’ll be going to the doctor to get checked out. Honesty and openness will reduce stress and anxiety about it and will make it easier to get help.”

The good news is that there are many treatments available, she says, depending on if you need to address medical problems that are causing ED, reducing the number or types of medicines you’re taking that lead to ED as a side effect, or treating the ED directly with pills, a penile erection pump, injectable medication, or surgery.

Dealing with erectile dysfunction from the start is the best thing that you can do for your relationship, your overall health, and your quality of life, she says.


Cialis - best drug for maximixing satisfaction

Cialis is one of the most popular and sold drugs on a worldwide basis and this unheralded success and popularity are not without a reason. The erectile dysfunction (ED) drug has the potential of “restoring” quality power and stamina within a short span of time. This safe and affordable ED drug is free from side effects, when used as per medical guidance, and can be purchased online without a prescription.

Also known as Tadalafil citrate, the erectile dysfunction drug is also a popular drug among professional sportsmen afflicted with a decline in sexual performance due to long-term use of low grade steroids or steroid abuse. Cialis is also recommended as an integral part of PCT (post cycle therapy) to restore the natural production of body hormones such as testosterone. Rated higher than Viagra and Levitra by some medical practitioners, Cialis holds good for 1-2 days as against a few hours of Viagra and Levitra.

When used in doses of 2-3 mg/day, after medical advice, Cialis can bring instant and long-lasting sexually satisfying results without putting users in proximity with any side effects. It is, however, important to note that Cialis should not be used in contravention or absence of medical advice and low grade Cialis should be not be used since that can lead to Cialis abuse and side effects such as facial flushing, muscle pain, and backache. In order to maintain its shelf life, Cialis is required to be stored at a controlled room temperature of 25°C (77°F) with excursions permitted up to 15-30°C (59-86°F).


Facts about Tribulus Terrestris

Tribulus Terrestris is a plant that grows in some moderate climates and tropical areas of the world. In studies, it has shown impressive results in enhancing natural testosterone levels over 40%. More testosterone in both males and females creates more lean muscle and higher levels of fat metabolism. Libido is also increased. Tribulus is a safe and effective way to increase testosterone production in your body.

Males: 750-1,500mg per day divided among meals.
Females: 250-750mg per day divided among meals.

Use Tribulus for 6-12 weeks followed by one month off. Use Tribulus for 4-8 weeks followed by one month off.
Most products come with their own instructions and should be followed.

Summary of Benifits
- Safe Elevation of Testosterone Levels
- Increased Muscle Growth
- Increased Strength and Endurance
- Quicker Recovery Between Workouts
- Increased Sleep Quality
- Increased Libido in both males and females


Proviron by Geneza Pharmaceuticals - sexual dysfunction

If you have been suffering from sexual dysfunction or have fears about this complication and avoided use of steroids for this reason only, Mesterolone or Proviron would be an excellent choice for you.

The orally applicable androgen and derivative of Dihydrotestosterone (DHT) was originally developed as a drug for treating depression in men. However, the drug soon gained prominence for treating problems during any stage of a normal sexual activity (sexual dysfunction).

Proviron has an anabolic-androgenic ratio of 100-150: 30-40 and can be detected over a period of 5-6 weeks. It can be purchased in the forms of tablets, capsules, injections, and even gels with or without a medical prescription.

This drug is best known for its ability to promote the quality and count of sperms besides treating low libido and erectile malfunction. Proviron is medically indicated to those suffering from testosterone deficiency or impotency. One of the biggest reasons why this drug is popular among sportsmen is because it helps in improving the release of luteinizing hormone and follicle-stimulating hormone to stimulate testes so that more testosterone can be produced.

Moreover, it has the unique potential of enhancing potency of testosterone in a steroid cycle where testosterone is one of the steroid cycle compounds. The recommended dose of Mesterolone is 25-100 mg per day for men and 25 mg every day for women and it is best stored at a controlled room temperature of 20° to 25°C (68° to 77°F) with excursions permitted to 15° to 30°C (59° to 86°F) and kept away from unauthorized use, pets, sunlight, moisture, and children.


Benefits of Cialis-Tadalafil Citrate advantages


If you want to give a new meaning to your sexual life, Cialis or Tadalafil citrate is the wonder drug you have been looking for. This drug for erectile dysfunction, a common complication with use of harsh and aromatizable steroids, is commonly used by sportsmen on steroids to come off an anabolic steroid cycle and augment low levels of testosterone.

This selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) is chemical designated as pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a- hexahydro-2-methyl-, (6R,12aR)-. Active ingredient in tablets of Cialis is Tadalafil citrate and the list of inactive ingredients includes magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, talc, titanium dioxide, croscarmellose sodium, hydroxypropyl cellulose, hypromellose, iron oxide, lactose monohydrate, and triacetin.

Since Cialis stays effective for forty eight to thirty six hours as compared to 5-8 hours of Viagra, it is more popular among people who want to uplift their sexual profile and life. This drug is medically indicated to individuals afflicted with pulmonary arterial hypertension and is best taken orally and preferably before 4 ½ hours before a sexual session. The recommended dose of Cialis is a tablet of 2.5 mg per day taken preferably at the same time every day for 5-7 days. It is very important to note that Cialis is not to be mistaken as a drug to protect a man or his partner from sexually transmitted disease and it does not serve as a male form of birth control and abuse of this drug can cause stomach upset, back pain, headache, and stuffy nose.


Sound sleep linked to lower prostate cancer risk


Men who sleep soundly are less likely to develop prostate cancer, a new study suggests.

Higher levels of melatonin, a hormone produced at night which helps regulate the body’s internal clock, were linked to a 75 per cent lower risk of developing an advanced form of the disease. Men who have trouble falling or staying asleep typically have lower levels of the hormone, suggesting that chronic disrupted sleep could raise the risk of the condition.

Researchers from the Harvard School of Public Health questioned 928 Icelandic men about their sleep patterns, and analysed urine samples for a marker linked to levels of melatonin.

Over a period of seven years 111 of the men were diagnosed with prostate cancer, including 24 with an “advanced” or life threatening form of the disease.

But those with above average melatonin marker levels were 75 per cent less likely to develop advanced prostate cancer than those with below average levels, according to results presented at an American Association for Cancer Research conference.

Sarah Markt, a research student who led the study, said: “Sleep loss and other factors can influence the amount of melatonin secretion or block it altogether, and health problems associated with low melatonin, disrupted sleep, and/or disruption of the circadian rhythm are broad, including a potential risk factor for cancer.”



Smoking can cause erectile dysfunction

The more men smoke, the higher their chances of experiencing erectile dysfunction, say the researchers. Led by Jiang He, professor of epidemiology at the Tulane University School of Public Health and Tropical Medicine, the researchers examined the association between cigarette smoking and erectile dysfunction in a 2000-2001 study in China that involved 7,684 men.

The surveyed men were between the ages of 35 to 74 and they did not have vascular disease. The researchers used questionnaires to assess the status of cigarette smoking and erectile dysfunction.

It was found that there was a significant statistical link between the number of cigarettes that men smoked and the likelihood that they would experience erectile dysfunction. This association was even stronger in participants with diabetes.

The study suggests that an estimated 22.7 percent of erectile dysfunction cases among Chinese men may be attributed to cigarette smoking.

Although erectile dysfunction is not a life-threatening condition, it affects well-being and quality of life. The researchers are of the opinion that smoking preventions may prove an important approach for reducing the risk of erectile dysfunction.


Erectile Dysfunction and Oral Medication Therapy

Viagra is a safe and effective oral treatment for men with erectile dysfunction of physical, psychological or mixed cause. However, it is important that patients should be aware of the low probability (less than 50%) that intercourse will be possible after the first dose - particularly in severe or advanced cases. The majority of men who stop Viagra because of apparent lack of effect will in fact respond and achieve intercourse if they continue to try, progress from 50 mg to 100 mg, or take the pill without food on an empty stomach (3 hours after eating).

Reliable safety data gathered in the 4 years since Viagra was launched confirm that side effects such as Priapism (prolonged erection), red eyes, painful eyes, syncope(fainting), tachycardia (rapid heart rate), and nausea do occur, but are rare. HIV medications (protease inhibitors) have been shown to raise Viagra blood levels. Certain patient groups are more susceptible to a decrease of their blood pressure, including those with aortic stenosis, hypertrophic obstructive cardiomyopathy, and multiple system atrophy. Finally, Viagra remains contraindicated in patients taking nitrates.

No new safety concerns have emerged in the past year, reinforcing that Viagra is very safe. Indeed, we now know that many patients with cardiovascular disease (CVD) and ED benefit from it.

The following can be prescribed Viagra safely without the need for extensive Cardiovascular investigation:

  • men who are a symptomatic and have fewer than three risk factors for coronary artery disease
  • those with controlled hypertension
  • those with mild stable angina
  • patients who have undergone successful coronary revascularisation (bypass or stent placement)
  • men with a history of uncomplicated heart attack that happened greater than 6-8 weeks ago
  • those with mild valvular disease of the heart
  • patients with mild left ventricular disease and congestive heart failure (NYHA Class I)

Alternative oral therapies for Erectile Dysfunction are Cialis (Tadalafil), Levitra (Vardenafil).

Viagra, Levitra and Cialis differ in their biochemical potency and selectivity, and in onset and duration of action, it is important not to extrapolate those findings inappropriately to the clinical setting. For example, greater biochemical potency does not necessarily translate into enhanced clinical efficacy. The same is true of selectivity.

The only clinically significant differences between Vigra, Levitra and Cialis are in duration and maximum concentration. Cialis’s half-life of 17.5 h makes it a “slow drug”, (not slow in onset) and explains why it does not interact with food. In general a medication for ED is effective for a period that equals two times the half life.

In short, there appears to be little biochemical or clinical differences between the three agents except for the lack of food interaction and the duration of activity for Cialis. All three medications are contraindicated in patients who take nitrates.

A recent survey looking at what patients with ED really want from their treatment found that efficacy and a favorable side-effect profile were the highest priorities.3 Fast onset was desirable, but there were major differences in what was considered fast. Duration was important only in terms of lasting long enough to complete intercourse. Few men (or their partners) felt that multiple erections, or the ability to achieve them over time, were critical as long as one dose was enough for a successful encounter. The majority of men already taking Viagra said it worked for them and had relatively consistent effects. Onset of action ranged from 15-75 min, and its duration was 6-8 h. Side-effects such as headache, flushing, and blue vision were well recognized and tolerated. Most complaints were about high cost or lack of insurance coverage.

An underlying desire was reported by most couples for initiation of sex to be normal (spontaneous and natural). Few patients fully understood the duration of activity that Viagra can provide, and its advantages. Cialis may indeed fulfill the desire that couples and patients with ED have for the initiation of sex to be normal (spontaneous and natural).

Although Viagra, Levitra and Cialis are safe and effective they do, like all medications, have disadvantages. They essentially enhance partial (sexual) erections, rather than initiating them. At best, the response rate among men with advanced ED (for example following radical prostatectomy) is 40%. Correct administration is critical, and if Viagra does not work when taken correctly, no other oral Viagra like drug (PDE5 inhibitor) will either.

In conclusion, the potencies of Viagra, Levitra and Cialis are broadly similar, but each has unique pharmacological properties related to its molecular structure. Viagra is an exemplary PDE-5 inhibitor that, after 4 years of widespread clinical use, is acknowledged to be effective and particularly well tolerated. The new medications are expected to be similar to Viagra in their efficacy and contraindications, but careful clinical evaluation will be necessary to ensure their safety. The only new attributes of clinical significance will be the lack of food interaction and the long duration of action of Cialis. This may translate into greater efficacy of the first dose as well as a return to more spontaneous (normal) initiation of sexual activity.


Sex After Menopause

A satisfying sex life is an important contributor to older adults’ quality of life, but the sexual pain that can come after menopause can rob women and their partners of that satisfaction. Treatment can help restore it, shows a global survey including some 1,000 middle-aged North American men and women, published online in Menopause, the journal of The North American Menopause Society (NAMS).

Sexual pain at this stage in a woman’s life is usually the result of the typical drying and thinning of tissues in and around the vagina after menopause, called vulvovaginal atrophy (VVA), coupled with a decrease in sexual activity. Vaginal lubricants and moisturizers, vaginal estrogen, and ospemifene, a recently approved oral drug that is a selective estrogen receptor modulator (SERM), can all be used to treat it.

Before treatment, a majority of these women (58%) said they had been avoiding intimacy because of the pain, and 68% said they had lost their desire because of it. An even higher percentage of the men (78%) thought their partner’s vaginal discomfort caused them to avoid intimacy. About a third of the men and women had stopped having sex altogether.

After treatment, a majority of women and men reported sex was less painful for them and their partner, and more than 40% of the women and men said sex was more satisfying. Twenty-nine percent of the women and 34% of the men said their sex life had improved. Treatment also had a positive impact on the women’s self esteem. About a third felt more optimistic about the future of their sex life, and a similar number felt more connected to their partners.

"There is no need for a woman’s quality of life to decline because of VVA," said NAMS Executive Director Margery L.S. Gass, MD.

Many women get relief with vaginal lubricants and moisturizers and regular sexual activity or the use of vaginal dilators. Vaginal estrogen, in the form of creams, tablets, or rings, is a common therapy and is appealing for women who cannot or choose not to take oral hormones, since absorption into the bloodstream is minimal. Women who have had breast or uterine cancer are encouraged to discuss the pros and cons of different treatments with their oncologist. The SERM offers an alternative for women who choose not to use any oral or vaginal hormone therapy.

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